Need - Immunosupression protocol
Medicine - Cellcept 750-0-750 mg
Effect - S developed excessive bloating. She had an upset stomach, was vomiting and in the end was completely dehydrated. Slowly she developed severe stomach ache. Creatinine shot up to 1.9. She had to get IV fluids inserted for a day and then stabilized. Endoscopy was also done to rule out gastro.
Substitute - Myfortic. S has adjusted well to this drug
Need - Immunosuppression protocol
Medicine - Wysolone 30/25/20/15 mg
Effect - S has got a lot of swelling on her face. She almost looks like an overfed child. She also has facial hair growth which was not there before. She has written about the emotional and psychological effect in another note.
Substitute - None. She has to bear it. The opinion is that these effects are reversible and will go away over a period of time as the dosage is reduced below 10 mg
Need - Immunosuppression protocol
Medicine - Tacrograf 1.5-0-1.0 mg
Effect - S had developed hypertension which she has never had. Even when the kidney functions were not optimum and deteriorating her BP was normal and under control. However that is not the case as of now. BP levels are between 124-132 / 84-92. She was originally taking Dilzem 60mg-0-0 and Selokon XL 25-0-0 to control the BP. Right now she has been advised to stop Dilzem and continue with the latter.
The other issue is that the doctors suspect that Tac is causing excessive toxicity which is preventing the creatinine levels from coming down. In order to address this, another drug has been introduced called Everolimus 0.25-0-0.25 mg and Tacrograf is being steadily cut down. Since the time Everolimus has been added, S has been complaining of some vertigo problems but the doctors believe it is not serious and should settle down in a couple of days. Tac will not be completely removed due to the rejection episode but after sometime Myfortic could be reduced and ultimately stopped.
Substitute - None.
Need - Treat UTI
Medicine - IV Ertapenam 1gm once a day
Effect - Caused a massive seizure within a few hours of administration. As soon as it was injected in the evening S was uncomfortable, spent a disturbed night and early morning had a seizure. The drug doesn't suit patients with central nervous disorders and should not be given to people with low seizure threshold levels.
Substitute- IV Meropenam 1 gm twice a day. This is a safer drug and very effective for UTI
Medicine - Cellcept 750-0-750 mg
Effect - S developed excessive bloating. She had an upset stomach, was vomiting and in the end was completely dehydrated. Slowly she developed severe stomach ache. Creatinine shot up to 1.9. She had to get IV fluids inserted for a day and then stabilized. Endoscopy was also done to rule out gastro.
Substitute - Myfortic. S has adjusted well to this drug
Need - Immunosuppression protocol
Medicine - Wysolone 30/25/20/15 mg
Effect - S has got a lot of swelling on her face. She almost looks like an overfed child. She also has facial hair growth which was not there before. She has written about the emotional and psychological effect in another note.
Substitute - None. She has to bear it. The opinion is that these effects are reversible and will go away over a period of time as the dosage is reduced below 10 mg
Need - Immunosuppression protocol
Medicine - Tacrograf 1.5-0-1.0 mg
Effect - S had developed hypertension which she has never had. Even when the kidney functions were not optimum and deteriorating her BP was normal and under control. However that is not the case as of now. BP levels are between 124-132 / 84-92. She was originally taking Dilzem 60mg-0-0 and Selokon XL 25-0-0 to control the BP. Right now she has been advised to stop Dilzem and continue with the latter.
The other issue is that the doctors suspect that Tac is causing excessive toxicity which is preventing the creatinine levels from coming down. In order to address this, another drug has been introduced called Everolimus 0.25-0-0.25 mg and Tacrograf is being steadily cut down. Since the time Everolimus has been added, S has been complaining of some vertigo problems but the doctors believe it is not serious and should settle down in a couple of days. Tac will not be completely removed due to the rejection episode but after sometime Myfortic could be reduced and ultimately stopped.
Substitute - None.
Need - Treat UTI
Medicine - IV Ertapenam 1gm once a day
Effect - Caused a massive seizure within a few hours of administration. As soon as it was injected in the evening S was uncomfortable, spent a disturbed night and early morning had a seizure. The drug doesn't suit patients with central nervous disorders and should not be given to people with low seizure threshold levels.
Substitute- IV Meropenam 1 gm twice a day. This is a safer drug and very effective for UTI
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